RMC-9805

A covalent inhibitor of KRASG12D

Product Specifications

CAS Number

2922732-54-3

Product Name Alternative

(2S) -2-cyclopentyl-2- ((S) -7- ((2R,3R) -3-cyclopropyl-1-methylaziridine-2-carbonyl) -2,7-diazaspiro[4.4]nonan-2-yl) -N- ((22S,63S,4S) -12- (5- (4-cyclopropylpiperazin-1-yl) -2- ((S) -1-methoxyethyl) pyridin-3-yl) -10,10-dimethyl-5,7-dioxo-11- (2,2,2-trifluoroethyl) -61,6

Synonyms

Zoldonrasib; KRAS G12D inhibitor 18

Purity

0.98

Smiles

O=C (OCC (C) (C) CC1=[C@@] ([C@@]2=C ([C@H] (C) OC) N=CC (N3CCN (C4CC4) CC3) =C2) N (CC (F) (F) F) C5=C1C=C6C=C5) [C@@H]7CCCN (C ([C@H] (C[C@H]8CN6CCO8) NC ([C@H] (C9CCCC9) N%10C[C@]%11 (CN (C ([C@H]%12[C@@H] (C%13CC%13) N%12C) =O) CC%11) CC%10) =O) =O) N7