RP03707

Product Specifications

CAS Number

3030493-05-8

SKU

C18324-5mg

Target

Ras

Applications

Apoptosis

Smiles

O=C1NC (CCN1C2=NN (C) C3=C2C=C (F) C (C4CCN (C5CC6 (CCN (CC7 (COC8=NC9=C (C=NC (C%10=C%11C (C#C) =C (F) C=CC%11=CC (O) =C%10) =C9F) C (N%12C[C@H]%13N[C@H] (CC%13) C%12) =N8) CC7) CC6) C5) CC4) =C3) =O

Molecular Formula

C55H58F3N11O4

Additionnal Information

RP03707 is a PROTAC molecule designed to degrade KRASG12D, consisting of three components: a KRASG12D inhibitor (, red), a linker (black), and an E3 ligase ligand (blue) .