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Chiglitazar (Carfloglitazar)

Product Specifications

CAS Number

743438-45-1

SKU

C18317-5mg

Target

PPAR

Applications

DNA Damage/DNA Repair

Smiles

O=C (C1=CC=C (F) C=C1) C (C=CC=C2) =C2N[C@H] (C (O) =O) CC (C=C3) =CC=C3OCCN4C5=CC=CC=C5C6=CC=CC=C46

Molecular Formula

C36H29FN2O4

Additionnal Information

Chiglitazar (Carfloglitazar) is a potent dual agonist of PPARα and PPARγ with EC50 values of 1.2 μM and 0.08 μM, respectively, and also activates PPARδ with an EC50 of 1.7 μM. It effectively improves insulin resistance and corrects dyslipidemia in monosodium L-glutamate (MSG) -induced obese rats.

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