Garcinone D

Product Specifications

CAS Number

107390-08-9

SKU

C18309-1mg

Target

STAT

Applications

Apoptosis

Molecular Formula

C24H28O7

Additionnal Information

Garcinone D is a natural xanthone from mangosteen, an activator of the STAT3/Cyclin D1 and Nrf2/HO-1 pathways, and an inhibitor of CDK2/CyclinE1 with an IC50 of 28.23 μM. It promotes neural stem cell proliferation via STAT3 and Nrf2/HO-1 activation while inhibiting prostate and breast cancer growth by blocking the CDK2/CyclinE1-mediated cell cycle and can be used in prostate and breast cancer research.