DS18561882
Product Specifications
CAS Number
2227149-22-4
SKU
C18296-1mg
Smiles
CS (=O) (NC1=CC=C (C (N2CCC (C3=CC=C (N4C[C@H] (C) N (C) CC4) C (C) =C3O5) =C (C5=O) C2) =O) C=C1OC (F) (F) F) =O
Molecular Formula
C28H31F3N4O6S
Additionnal Information
DS18561882 is a potent, isozyme-selective, and orally available inhibitor of methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) with an IC50 value of 0.0063 μM. It exhibits complete tumor growth inhibition in a mouse xenograft model, and shows potential as an anti-cancer agent.
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1035639-01 0.02 mg (E-Coli)
Recombinant Rhizobium leguminosarum bv.trifolii Peptidyl-tRNA hydrolase (pth)
Ask
View Details MBS1035639-02 0.1 mg (E-Coli)
Recombinant Rhizobium leguminosarum bv.trifolii Peptidyl-tRNA hydrolase (pth)
Ask
View Details MBS1035639-03 0.02 mg (Yeast)
Recombinant Rhizobium leguminosarum bv.trifolii Peptidyl-tRNA hydrolase (pth)
Ask
View Details