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Simurosertib

Product Specifications

CAS Number

1330782-76-7

Synonyms

TAK-931

SKU

C18243-25mg

Target

CDK

Applications

Cell Cycle

Smiles

CC1=C (C=NN1) C2=CC3=C (S2) C (=O) NC (=N3) C4CC5CCN4CC5

Molecular Formula

C17H19N5OS

Additionnal Information

Simurosertib (TAK-931), an oral cell division cycle 7 (CDC7) -selective inhibitor with an IC50<0.3 nM, induces S phase delay and replication stress and causes mitotic aberrations through centrosome dysregulation and chromosome missegregation, resulting in irreversible antiproliferative effects in cancer cells.

Storage Conditions

3 years -20°C powder

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