ML221
Product Specifications
CAS Number
877636-42-5
SKU
C18213-25mg
Target
Angiotensin Receptor
Applications
GPCR & G Protein
Smiles
C1=CN=C (N=C1) SCC2=CC (=O) C (=CO2) OC (=O) C3=CC=C (C=C3) [N+] (=O) [O-]
Molecular Formula
C17H11N3O6S
Additionnal Information
ML221 is a potent apelin receptor (APJ) functional antagonist in cell-based assays that is >37-fold selective over the closely related angiotensin II type 1 (AT1) receptor. The IC50 values of ML221 are 0.70 and 1.75 μM in a cAMP assay and β-arrestin assay, respectively.
Storage Conditions
2 years -80 in solvent
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