PF-06409577
Product Specifications
CAS Number
1467057-23-3
SKU
C18166-25mg
Target
AMPK
Applications
PI3K/Akt/mTOR
Smiles
C1CC (C1) (C2=CC=C (C=C2) C3=C (C=C4C (=C3) C (=CN4) C (=O) O) Cl) O
Molecular Formula
C19H16ClNO3
Additionnal Information
PF-06409577 is an orally bioavailable AMPK activator with EC50 of 7 nM for α1β1γ1 in the TR-FRET assay and it shows no detectable inhibition of hERG in a patch-clamp assay (100 μM) and was not an inhibitor (IC50 > 100 μM) of the microsomal activities of major human cytochrome P450 isoforms.
Storage Conditions
2 years -80 in solvent
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