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Kobe0065

Product Specifications

CAS Number

436133-68-5

SKU

C18155-200mg

Target

Ras

Applications

Apoptosis

Smiles

CC1=C (C=C (C=C1) NC (=S) NNC2=C (C=C (C=C2[N+] (=O) [O-]) C (F) (F) F) [N+] (=O) [O-]) Cl

Molecular Formula

C15H11ClF3N5O4S

Additionnal Information

Kobe0065 is an H-Ras-cRaf1 interaction inhibitor, exhibiting potent activity to competitively inhibit the binding of H-Ras·GTP to c-Raf-1 RBD with a Ki value of 46 ± 13 μM.

Storage Conditions

2 years -80 in solvent

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