Tenovin-1

Product Specifications

CAS Number

380315-80-0

SKU

C18082-10mM/1mL

Target

P53

Applications

Apoptosis

Smiles

CC (=O) NC1=CC=C (C=C1) NC (=S) NC (=O) C2=CC=C (C=C2) C (C) (C) C

Molecular Formula

C20H23N3O2S

Additionnal Information

Tenovin-1 protects against MDM2-mediated p53 degradation, which involves ubiquitination, and acts through inhibition of protein-deacetylating activities of SirT1 and SirT2. Tenovin-1 is also an inhibitor of dihydroorotate dehydrogenase (DHODH) .

Storage Conditions

2 years -80 in solvent

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