NVP-CGM097
Product Specifications
CAS Number
1313363-54-0
Synonyms
CGM-097
SKU
C18057-25mg
Target
MDM2/MDMX
Applications
Apoptosis
Smiles
CC (C) OC1=C (C=C2CC (=O) N (C (C2=C1) C3=CC=C (C=C3) Cl) C4=CC=C (C=C4) N (C) CC5CCC (CC5) N6CCN (C (=O) C6) C) OC
Molecular Formula
C38H47ClN4O4
Additionnal Information
NVP-CGM097 is a highly potent and selective MDM2 inhibitor with Ki value of 1.3 nM for hMDM2 in TR-FRET assay. It binds to the p53 binding-site of the Mdm2 protein, disrupting the interaction between both proteins, leading to an activation of the p53 pathway.
Storage Conditions
2 years -80 in solvent
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