BI-847325

Product Specifications

CAS Number

1207293-36-4

SKU

C18048-100mg

Target

MEK

Applications

Protein Tyrosine Kinase

Smiles

CCNC (=O) C#CC1=CC2=C (C=C1) C (=C (N2) O) C (=NC3=CC=C (C=C3) CN (C) C) C4=CC=CC=C4

Molecular Formula

C29H28N4O2

Additionnal Information

BI-847325 is an orally bioavailable, and selective dual MEK/Aurora kinase inhibitor with IC50 of 3 nM, 25 nM, 15 nM, 25 nM, and 4 nM for Xenopus laevis Aurora B, human Aurora A and Aurora C, as well as human MEK1 and MEK2, respectively. Phase 1.

Storage Conditions

2 years -80 in solvent

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