WH-4-023
Product Specifications
CAS Number
837422-57-8
Synonyms
KIN001-112, KIN112, Dual LCK/SRC inhibitor
SKU
C17986-100mg
Target
Src
Applications
Protein Tyrosine Kinase
Smiles
CC1=C (C (=CC=C1) C) OC (=O) N (C2=C (C=C (C=C2) OC) OC) C3=NC (=NC=C3) NC4=CC=C (C=C4) N5CCN (CC5) C
Molecular Formula
C32H36N6O4
Additionnal Information
WH-4-023 (KIN001-112, KIN112, Dual LCK/SRC inhibitor) is a potent and orally active Lck/Src inhibitor with IC50s of 2 nM and 6 nM in cell-free assays, respectively. Exhibits >300-fold selectivity against p38α and KDR. Also potently inhibits SIK (IC50 values are 10, 22 and 60 nM for SIK 1, 2 and 3 respectively) and displays selectivity over a range of closely related kinases.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15259995 1 Vial
Lentiviral mouse Specc1 shRNA (UAS) - Lentiviral mouse Specc1 shRNA (UAS, iRFP) (100)
Sign In for Pricing
View Details 
N2904-35D-AP 100 µL
NMDA 2b Receptor (NMDA R2b, N-methyl-D-aspartate, GRIN2B, Glutamate receptor ionotropic N-methyl D-aspartate 2B, HGNC:4586, NR2B, hNR3, N-methyl-D-aspartate receptor subunit 2B) (AP) discontinued
Sign In for Pricing
View Details 
MBS1034027-01 0.02 mg (E-Coli)
Recombinant Variovorax paradoxus Peptide chain release factor 1 (prfA)
Sign In for Pricing
View Details MBS1034027-02 0.02 mg (Yeast)
Recombinant Variovorax paradoxus Peptide chain release factor 1 (prfA)
Sign In for Pricing
View Details