Lorlatinib (PF-6463922)
Product Specifications
CAS Number
1454846-35-5
SKU
C17977-10mM/1mL
Target
ALK
Applications
Protein Tyrosine Kinase
Smiles
CC1C2=C (C=CC (=C2) F) C (=O) N (CC3=NN (C (=C3C4=CC (=C (N=C4) N) O1) C#N) C) C
Molecular Formula
C21H19FN6O2
Additionnal Information
Lorlatinib (PF-6463922) is a potent, dual ALK/ROS1 inhibitor with Ki of <0.02 nM, <0.07 nM, and 0.7 nM for ROS1, ALK (WT), and ALK (L1196M), respectively. PF-06463922 induces apoptosis. Phase 1.
Storage Conditions
2 years -80 in solvent
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![SSX5 Mouse Monoclonal Antibody [Clone ID: OTI1H1]](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
T3210 1x106 cells / 1.0 mL
Mutant AKT1 Stable Proteus Syndrome Derived Cell Line (F6B)
Sign In for Pricing
View Details NBP1-76705JF549 0.1 mL
Rabbit Polyclonal RP105/CD180 Antibody [Janelia Fluor 549]
Sign In for Pricing
View Details