Birabresib (OTX015)
Product Specifications
CAS Number
202590-98-5
Synonyms
MK 8628
SKU
C17931-100mg
Target
Epigenetic Reader Domain
Applications
Epigenetics
Smiles
CC1=C (SC2=C1C (=NC (C3=NN=C (N32) C) CC (=O) NC4=CC=C (C=C4) O) C5=CC=C (C=C5) Cl) C
Molecular Formula
C25H22ClN5O2S
Additionnal Information
Birabresib (OTX015, MK 8628) is a potent BET bromodomain inhibitor with EC50 ranging from 10 to 19 nM for BRD2, BRD3, and BRD4 in cell-free assays. Birabresib inhibits the expression of Nuclear receptor binding SET domain protein 3 (NSD3) target genes.
Storage Conditions
2 years -80 in solvent
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