Fruquintinib
Product Specifications
CAS Number
1194506-26-7
Synonyms
HMPL-013
SKU
C17642-100mg
Target
VEGFR
Applications
Protein Tyrosine Kinase
Smiles
CC1=C (C2=C (O1) C=C (C=C2) OC3=NC=NC4=CC (=C (C=C43) OC) OC) C (=O) NC
Molecular Formula
C21H19N3O5
Additionnal Information
Fruquintinib is a small molecule inhibitor with strong potency and high selectivity against VEGFR family. It inhibits VEGFR 1, 2, 3, with IC50 values of 33 nM, 35 nM and 0.5 nM, respectively and shows only weak inhibition of RET, FGFR-1 and c-kit kinases.
Storage Conditions
3 years -20°C powder
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