NU2058

Product Specifications

CAS Number

161058-83-9

Synonyms

O (6) -Cyclohexylmethylguanine

SKU

C17609-25mg

Target

CDK

Applications

Cell Cycle

Smiles

C1CCC (CC1) COC2=NC (=NC3=C2NC=N3) N

Molecular Formula

C12H17N5O

Additionnal Information

NU2058 (O (6) -Cyclohexylmethylguanine) is an inhibitor of CDK2 with IC50 value of 17 μM in an isolated enzyme assay. It also potentiates melphalan (DMF 2.3), and monohydroxymelphalan (1.7), but not temozolomide or ionising radiation.

Storage Conditions

2 years -80 in solvent

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