Aurora Kinase Inhibitor III
Product Specifications
CAS Number
879127-16-9
SKU
C17155-5mg
Target
Aurora Kinase
Applications
Cell Cycle
Smiles
C1CC1C (=O) NC2=CC=CC (=C2) NC3=NC=CC (=N3) NC4=CC=CC (=C4) C (F) (F) F
Molecular Formula
C21H18F3N5O
Additionnal Information
Aurora kinase inhibitor III is a potent inhibitor of Aurora A kinase with an IC50 of 42 nM and has high selectivity for Aurora A over BMX, BTK, IGF-1R, c-Src, TRKB, SYK, and EGFR (IC50s = 386, 3,550, 591, 1,980, 2,510, 887, and >10,000 nM, respectively) .
Storage Conditions
3 years -20°C powder
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