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WHI-P154

Product Specifications

CAS Number

211555-04-3

SKU

C17116-10mM/1mL

Target

EGFR

Applications

Protein Tyrosine Kinase

Smiles

COC1=C (C=C2C (=C1) C (=NC=N2) NC3=CC (=C (C=C3) O) Br) OC

Molecular Formula

C16H14BrN3O3

Additionnal Information

WHI-P154 is a potent JAK3 inhibitor with IC50 of 1.8 μM, no activity against JAK1 or JAK2, also inhibits EGFR, Src, Abl, VEGFR and MAPK, prevents Stat3, but not Stat5 phosphorylation.

Storage Conditions

2 years -80 in solvent

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