What is the catalog number for MK-5108?

The catalog number for MK-5108 is C17055.

What sizes are available for MK-5108?

MK-5108 is available in the following size(s): 10 mg, 200 mg.

How many pack sizes does MK-5108 come in?

MK-5108 is available in 2 different pack sizes.

MK-5108 is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for MK-5108?

MK-5108 is requires dry ice shipping.

MK-5108

Product Specifications

CAS Number

1010085-13-8

Synonyms

VX-689

SKU

C17055-10mg

Target

Aurora Kinase

Applications

Cell Cycle

Smiles

C1CC (CCC1OC2=C (C (=CC=C2) Cl) F) (CC3=NC (=CC=C3) NC4=NC=CS4) C (=O) O

Molecular Formula

C22H21ClFN3O3S

Additionnal Information

MK-5108 is a highly selective Aurora A inhibitor with IC50 of 0.064 nM in a cell-free assay and is 220- and 190-fold more selective for Aurora A than Aurora B/C, while it inhibits TrkA with less than 100-fold selectivity. MK-5108 (VX-689) induces autophagy. Phase 1.