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Dinaciclib

Product Specifications

CAS Number

779353-01-4

Synonyms

SCH727965, PS-095760

SKU

C17054-25mg

Target

CDK

Applications

Cell Cycle

Smiles

CCC1=C2N=C (C=C (N2N=C1) NCC3=C[N+] (=CC=C3) [O-]) N4CCCCC4CCO

Molecular Formula

C21H28N6O2

Additionnal Information

Dinaciclib is a novel and potent CDK inhibitor for CDK2, CDK5, CDK1 and CDK9 with IC50 of 1 nM, 1 nM, 3 nM and 4 nM in cell-free assays, respectively. It also blocks thymidine (dThd) DNA incorporation. Dinaciclib induces apoptosis through the activation of caspases 8 and 9. Phase 3.

Storage Conditions

2 years -80 in solvent

Available Sizes

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