BGT226 (NVP-BGT226) maleate

1245537-68-1

C17042-10mg

MTOR

PI3K/Akt/mTOR

CN1C2=CN=C3C=CC (=CC3=C2N (C1=O) C4=CC (=C (C=C4) N5CCNCC5) C (F) (F) F) C6=CN=C (C=C6) OC.C (=CC (=O) O) C (=O) O

C28H25F3N6O2.C4H4O

BGT226 (NVP-BGT226) maleate is a novel class I PI3K/mTOR inhibitor for PI3Kα/β/γ with IC50 of 4 nM/63 nM/38 nM. Phase 1/2.

2 years -80 in solvent