AZ 628
Product Specifications
CAS Number
878739-06-1
SKU
C17039-10mM/1mL
Target
Raf
Applications
MAPK
Smiles
CC1=C (C=C (C=C1) NC (=O) C2=CC (=CC=C2) C (C) (C) C#N) NC3=CC4=C (C=C3) N=CN (C4=O) C
Molecular Formula
C27H25N5O2
Additionnal Information
AZ628 is a new pan-Raf inhibitor for BRAF, BRAFV600E, and c-Raf-1 with IC50 of 105 nM, 34 nM and 29 nM in cell-free assays, also inhibits VEGFR2, DDR2, Lyn, Flt1, FMS, etc. AZ628 induces apoptosis.
Storage Conditions
2 years -80 in solvent
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