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PF-04691502

Product Specifications

CAS Number

1013101-36-4

Synonyms

PF4691502

SKU

C17037-10mg

Target

Akt

Applications

PI3K/Akt/mTOR

Smiles

CC1=C2C=C (C (=O) N (C2=NC (=N1) N) C3CCC (CC3) OCCO) C4=CN=C (C=C4) OC

Molecular Formula

C22H27N5O4

Additionnal Information

PF-04691502 (PF4691502) is an ATP-competitive PI3K (α/β/δ/γ) /mTOR dual inhibitor with Ki of 1.8 nM/2.1 nM/1.6 nM/1.9 nM and 16 nM in cell-free assays, little activity against either Vps34, AKT, PDK1, p70S6K, MEK, ERK, p38, or JNK. PF-04691502 induces apoptosis. Phase 2.

Storage Conditions

2 years -80 in solvent

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