What is the catalog number for Apitolisib (GDC-0980)?

The catalog number for Apitolisib (GDC-0980) is C17010.

What sizes are available for Apitolisib (GDC-0980)?

Apitolisib (GDC-0980) is available in the following size(s): 10 mg, 200 mg.

How many pack sizes does Apitolisib (GDC-0980) come in?

Apitolisib (GDC-0980) is available in 2 different pack sizes.

Is Apitolisib (GDC-0980) in stock?

Apitolisib (GDC-0980) is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for Apitolisib (GDC-0980)?

Apitolisib (GDC-0980) is requires dry ice shipping.

Apitolisib (GDC-0980)

Product Specifications

CAS Number

1032754-93-0

Synonyms

RG7422, GNE 390

SKU

C17010-200mg

Target

MTOR

Applications

PI3K/Akt/mTOR

Smiles

CC1=C (SC2=C1N=C (N=C2N3CCOCC3) C4=CN=C (N=C4) N) CN5CCN (CC5) C (=O) C (C) O

Molecular Formula

C23H30N8O3S

Additionnal Information

Apitolisib (GDC-0980, RG7422, GNE 390) is a potent, class I PI3K inhibitor for PI3Kα/β/δ/γ with IC50 of 5 nM/27 nM/7 nM/14 nM in cell-free assays, respectively. Also a mTOR inhibitor with Ki of 17 nM in a cell-free assay, and highly selective versus other PIKK family kinases. Apitolisib activates autophagy and apoptosis simultaneously in pancreatic cancer cells. Phase 2.