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Itraconazole

Product Specifications

CAS Number

84625-61-6

Synonyms

R 51211

SKU

C16864-100mg

Target

Hedgehog/Smoothened

Applications

Stem Cells & Wnt

Smiles

CCC (C) N1C (=O) N (C=N1) C2=CC=C (C=C2) N3CCN (CC3) C4=CC=C (C=C4) OCC5COC (O5) (CN6C=NC=N6) C7=C (C=C (C=C7) Cl) Cl

Molecular Formula

C35H38Cl2N8O4

Additionnal Information

Itraconazole is a relatively potent inhibitor of CYP3A4 with IC50 of 6.1 nM, used as a triazole antifungal agent. Itraconazole is a potent antagonist of the Hedgehog (Hh) signaling pathway. Itraconazole suppresses the growth of glioblastoma through induction of autophagy.

Storage Conditions

2 years -80 in solvent

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