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PCI-34051

Product Specifications

CAS Number

950762-95-5

SKU

C16585-100mg

Target

HDAC

Applications

DNA Damage/DNA Repair

Smiles

COC1=CC=C (C=C1) CN2C=CC3=C2C=C (C=C3) C (=O) NO

Molecular Formula

C17H16N2O3

Additionnal Information

PCI-34051 is a potent and specific HDAC8 inhibitor with IC50 of 10 nM in a cell-free assay. It has greater than 200-fold selectivity over HDAC1 and 6, more than 1000-fold selectivity over HDAC2, 3, and 10. PCI-34051 induces caspase-dependent apoptosis.

Storage Conditions

2 years -80 in solvent

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