Hesperadin

Product Specifications

CAS Number

422513-13-1

SKU

C16371-10mg

Target

Aurora Kinase

Applications

Cell Cycle

Smiles

CCS (=O) (=O) NC1=CC2=C (C=C1) NC (=C2C (=NC3=CC=C (C=C3) CN4CCCCC4) C5=CC=CC=C5) O

Molecular Formula

C29H32N4O3S

Additionnal Information

Hesperadin potently inhibits Aurora B with IC50 of 250 nM in a cell-free assay. It markedly reduces the activity of AMPK, Lck, MKK1, MAPKAP-K1, CHK1 and PHK while it does not inhibit MKK1 activity in vivo.

Storage Conditions

2 years -80 in solvent

Available Sizes

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