Tipifarnib

Product Specifications

CAS Number

192185-72-1

Synonyms

R115777, IND 58359

SKU

C16323-200mg

Target

Transferase

Applications

Metabolism

Smiles

CN1C=NC=C1C (C2=CC=C (C=C2) Cl) (C3=CC4=C (C=C3) N (C (=O) C=C4C5=CC (=CC=C5) Cl) C) N

Molecular Formula

C27H22Cl2N4O

Additionnal Information

Tipifarnib is a potent and specific farnesyltransferase (FTase) inhibitor with IC50 of 0.6 nM, its anti-proliferative effects are most prominent in H-ras or N-ras mutant cells. Phase 3.

Storage Conditions

2 years -80 in solvent

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