Decitabine (5-Aza-2'-Deoxycytidine)

Product Specifications

CAS Number

2353-33-5

Synonyms

Deoxycytidine, 5-aza-2'-deoxycytidine, 5-AZA-dC, 5-aza-CdR, NSC 127716

SKU

C16182-50mg

Target

DNA Methyltransferase

Applications

Epigenetics

Smiles

C1C (C (OC1N2C=NC (=NC2=O) N) CO) O

Molecular Formula

C8H12N4O4

Additionnal Information

Decitabine is a DNA methyltransferase inhibitor, incorporating into DNA and resulting in hypomethylation of DNA and intra-S-phase arrest of DNA replication. It is used to treat myelodysplastic syndrome (MDS) . Decitabine induces cell cycle arrest and apoptosis in various cancer cell lines.