CYC116

Product Specifications

CAS Number

693228-63-6

SKU

C16159-200mg

Target

Aurora Kinase

Applications

Cell Cycle

Smiles

CC1=C (SC (=N1) N) C2=NC (=NC=C2) NC3=CC=C (C=C3) N4CCOCC4

Molecular Formula

C18H20N6OS

Additionnal Information

CYC116 is a potent inhibitor of Aurora A/B with Ki of 8.0 nM/9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not active against PKA, Akt/PKB, PKC, no effect on GSK-3α/β, CK2, Plk1 and SAPK2A. Phase 1.

Storage Conditions

2 years -80 in solvent

Available Sizes

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