Onalespib (AT13387)

912999-49-6

C16153-10mg

HSP (HSP90)

Cytoskeletal Signaling

CC (C) C1=CC (=C (C=C1O) O) C (=O) N2CC3=C (C2) C=C (C=C3) CN4CCN (CC4) C

C24H31N3O3

Onalespib (AT13387) is a selective potent Hsp90 inhibitor with IC50 of 18 nM in A375 cells, displays a long duration of anti-tumor activity. Phase 2.

2 years -80 in solvent