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TAE684 (NVP-TAE684)

Product Specifications

CAS Number

761439-42-3

SKU

C16115-10mg

Target

ALK

Applications

Protein Tyrosine Kinase

Smiles

CC (C) S (=O) (=O) C1=CC=CC=C1NC2=NC (=NC=C2Cl) NC3=C (C=C (C=C3) N4CCC (CC4) N5CCN (CC5) C) OC

Molecular Formula

C30H40ClN7O3S

Additionnal Information

TAE684 (NVP-TAE684) is a potent and selective ALK inhibitor which blocked the growth of ALCL-derived and ALK-dependent cell lines with IC50 values between 2 and 10 nM, 100-fold more sensitive for ALK than InsR. TAE684 (NVP-TAE684) induces cell cycle arrest and apoptosis.

Storage Conditions

2 years -80 in solvent

Available Sizes

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