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Mipomersen

Product Specifications

CAS Number

1000120-98-8

Synonyms

ISIS 301012 free base

SKU

C15164-1mg

Target

HCV

Applications

Microbiology

Additionnal Information

Mipomersen (ISIS 301012 free base) is an antisense oligonucleotide inhibitor of apolipoprotein B-100 (apoB-100) that causes selective degradation of apoB-100 mRNA, thereby inhibiting protein translation. This leads to reductions in low-density lipoprotein cholesterol (LDL-C) and other apoB-containing lipoprotein levels. Mipomersen is used as an adjunct treatment for homozygous familial hypercholesterolemia (FH) .

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