What is the catalog number for Safusidenib?

The catalog number for Safusidenib is C15153.

What sizes are available for Safusidenib?

Safusidenib is available in the following size(s): 5 mg, 25 mg, 100 mg, 1 g.

How many pack sizes does Safusidenib come in?

Safusidenib is available in 4 different pack sizes.

Is Safusidenib in stock?

Safusidenib is currently made to order / not held in immediate stock. Contact us for lead time.

Safusidenib

Product Specifications

CAS Number

1898206-17-1

Synonyms

AB-291; DS-1001

SKU

C15153-5mg

Smiles

O=C (N1C2=CC=CC (/C=C/C (O) =O) =C2C (C) =C1) C3=C (C (C) (F) C) ON=C3C4=C (C=C (C=C4Cl) Cl) Cl

Molecular Formula

C25H18Cl3FN2O4

Additionnal Information

Safusidenib (AB-291; DS-1001) is an orally bioavailable, selective inhibitor of mutant IDH1. It demonstrates potent inhibition against mutant IDH1 while showing minimal activity against the wild-type enzyme. The compound exhibits antitumor effects in chondrosarcoma models. In vitro assays without preincubation, safusidenib inhibits IDH1R132H and IDH1R132C with IC50 values of 15 nM and 130 nM, respectively.