JG-2016
Product Specifications
CAS Number
2887480-87-5
SKU
C15120-5mg
Target
Histone Acetyltransferase
Applications
Epigenetics
Molecular Formula
C18H21ClN4O3
Additionnal Information
JG-2016 is a potent and selective inhibitor of HAT1, with an IC50 of 14.8 μM and a binding KD of 22.5 μM for the HAT1:Rbap46 complex. It exhibits anti-proliferative activity with EC50 of 10.4 μM, 29.8 μM, and 1.9 μM in HCC1806, FICC1937, and A549 cells, respectively. JG-2016 significantly suppresses tumor growth in an A549 xenograft model.
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