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SKLB-197

Product Specifications

CAS Number

2713577-16-1

SKU

C14696-25mg

Target

ATM/ATR

Applications

PI3K/Akt/mTOR

Smiles

CC1COCCN1C2=NC (=NC3=C2C=C (C=C3) C4=CC=N[N]4C) C5=C6C=C[NH]C6=CC=C5

Molecular Formula

C25H24N6O

Additionnal Information

SKLB-197 exerts selectively inhibition against ataxia telangiectasia mutated and Rad3-related (ATR) kinase with IC50 of 0.013 μM, also displays potent antitumor activity against ATM-deficent tumors both in vitro and in vivo.

Storage Conditions

3 years -20°C powder

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