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GS-621763

Product Specifications

CAS Number

2647442-13-3

SKU

C14695-25mg

Target

SARS-CoV

Applications

Microbiology

Smiles

CC (C) C (=O) OCC1OC (C#N) (C (OC (=O) C (C) C) C1OC (=O) C (C) C) C2=CC=C3[N]2N=CN=C3N

Molecular Formula

C24H31N5O7

Additionnal Information

GS-621763, an orally bioavailable prodrug of GS-441524, shows a dose-dependent antiviral effect on SARS-CoV-2 reporter virus expressing nanoluciferase (SARS-CoV-2 nLUC) replication with an EC50 of 2.8 μM, also inhibits reporter SARS-CoV-2 expressing firefly luciferase (SARS-CoV-2 Fluc) replication with EC50 of 0.125 μM.

Storage Conditions

3 years -20°C powder

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