DCPIB
Product Specifications
CAS Number
82749-70-0
SKU
C14627-25mg
Target
Potassium Channel
Applications
Transmembrane Transporters
Smiles
CCCCC1 (CC2=CC (=C (Cl) C (=C2C1=O) Cl) OCCCC (O) =O) C3CCCC3
Molecular Formula
C22H28Cl2O4
Additionnal Information
DCPIB is a specific and potent inhibitor of volume-regulated anion channels (VRAC) . DCPIB potently inhibits several K2P channels with no voltage dependence, including TRESK, TASK1, and TASK3. DCPIB displayed superior selectivity toward TRESK with an IC50 of 0.14 μM, demonstrating at least 100-fold higher affinity over TREK1/TRAAK channels. DCPIB is also a novel selective blocker of I (Cl, swell), which blocks native I (Cl, swell) of calf bovine pulmonary artery endothelial (CPAE) cells with an IC (50) of 4.1 μM.
Storage Conditions
3 years -20°C powder
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS1045361-01 0.02 mg (E-Coli)
Recombinant Arabidopsis thaliana Ethylene-responsive transcription factor RAP2-3 (RAP2-3)
Sign In for Pricing
View Details 
MBS1045361-02 0.1 mg (E-Coli)
Recombinant Arabidopsis thaliana Ethylene-responsive transcription factor RAP2-3 (RAP2-3)
Sign In for Pricing
View Details 
MBS1045361-03 0.02 mg (Yeast)
Recombinant Arabidopsis thaliana Ethylene-responsive transcription factor RAP2-3 (RAP2-3)
Sign In for Pricing
View Details MBS1045361-04 0.1 mg (Yeast)
Recombinant Arabidopsis thaliana Ethylene-responsive transcription factor RAP2-3 (RAP2-3)
Sign In for Pricing
View Details MBS1045361-05 0.02 mg (Baculovirus)
Recombinant Arabidopsis thaliana Ethylene-responsive transcription factor RAP2-3 (RAP2-3)
Sign In for Pricing
View Details MBS1045361-06 0.02 mg (Mammalian-Cell)
Recombinant Arabidopsis thaliana Ethylene-responsive transcription factor RAP2-3 (RAP2-3)
Sign In for Pricing
View Details