STM2457

Product Specifications

CAS Number

2499663-01-1

SKU

C14515-5mg

Target

Transferase

Applications

Metabolism

Smiles

O=C (NCC1=C[N]2C=C (CNCC3CCCCC3) C=CC2=N1) C4=CC (=O) N5C=CC=CC5=N4

Molecular Formula

C25H28N6O2

Additionnal Information

STM2457 is a highly potent and selective first-in-class catalytic inhibitor of RNA Methyltransferase METTL3 with an IC50 of 16.9 nM. STM2457 is highly specific for METTL3 and showed no inhibition of other RNA methyltransferases.

Storage Conditions

3 years -20°C powder

Available Sizes

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