TPX-0046

2359650-19-2

C14488-1mg

C-RET

Protein Tyrosine Kinase

CC1CNC (=O) C2=C3N=C4N (CC5=C (O1) N=CC (=C5) F) C6CCCC6OC4=C[N]3N=C2

C21H21FN6O3

TPX-0046 is a novel RET/SRC inhibitor with a mean IC50 of 17 nM for RETG810R in Ba/F3 cell proliferation assay.

3 years -20°C powder