What is the catalog number for JHU37160?

The catalog number for JHU37160 is C14472.

What sizes are available for JHU37160?

JHU37160 is available in the following size(s): 25 mg.

Is JHU37160 in stock?

JHU37160 is currently made to order / not held in immediate stock. Contact us for lead time.

JHU37160

Product Specifications

CAS Number

2369979-68-8

SKU

C14472-25mg

Target

AChR

Applications

Neuronal Signaling

Smiles

CCN1CCN (CC1) C2=NC3=CC (=CC=C3NC4=C2C=CC=C4F) Cl

Molecular Formula

C19H20ClFN4

Additionnal Information

JHU37160 is a Designer Receptors Exclusively Activated by Designer Drug (DREADD) agonist with Ki of 1.9 nM and 3.6 nM for human muscarinic acetylcholine M3 receptors (hM3Dq) and hM4Di in vitro, respectively. And EC50 values are 18.5 nM and 0.2 nM for hM3Dq and hM4Di in fluorescent and BRET-based assays in HEK-293 cells, respectively.