ME-344

Product Specifications

CAS Number

1374524-68-1

SKU

C14453-5mg

Target

OXPHOS

Applications

Apoptosis

Molecular Formula

C22H20O4

Additionnal Information

ME-344 is a synthetic metabolite of NV-128, a potent inhibitor of mitochondrial oxidative phosphorylation (OXPHOS) complex I, disrupting ATP generation and oxygen consumption. It also inhibits mTOR by downregulating the AKT/mTOR pathway, exhibiting anticancer activity by inhibiting cell growth and viability in leukemia cell lines with IC50 values of 70–260 nM.