Rimiducid (AP1903)
Product Specifications
CAS Number
195514-63-7
SKU
C14444-5mg
Target
FKBP
Applications
Apoptosis
Smiles
CCC (C (=O) N1CCCCC1C (=O) OC (CCC2=CC (=C (OC) C=C2) OC) C3=CC (=CC=C3) OCC (=O) NCCNC (=O) COC4=CC=CC (=C4) C (CCC5=CC (=C (OC) C=C5) OC) OC (=O) C6CCCCN6C (=O) C (CC) C7=CC (=C (OC) C (=C7) OC) OC) C8=CC (=C (OC) C (=C8) OC) OC
Molecular Formula
C78H98N4O20
Additionnal Information
Rimiducid (AP1903) is a chemical protein dimerizer and binds tightly to the target FKBP fusion protein while binding minimally to the abundant natural FKBP. Rimiducid elicites potent and dose-dependent apoptosis of cells in culture expressing dimerizer-dependent Fas constructs, with an EC50 of ≈0.1 nM.
Storage Conditions
3 years -20°C powder
Available Sizes
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