CDDO-Im (RTA-403)

Product Specifications

CAS Number

443104-02-7

Synonyms

CDDO-Imidazolide, TP-235

SKU

C14441-5mg

Target

Nrf2

Applications

NF-κB

Smiles

CC1 (C) CCC2 (CCC3 (C) C (C2C1) C (=O) C=C4C5 (C) C=C (C#N) C (=O) C (C) (C) C5CCC34C) C (=O) [N]6C=CN=C6

Molecular Formula

C34H43N3O3

Additionnal Information

CDDO-Im (RTA-403) is an activator of nuclear factor erythroid 2–related factor 2 (Nrf2) and peroxisome proliferator-activated receptor (PPAR) . CDDO-Im binds to PPARα and PPARγ with Ki of 232 nM and 344 nM, respectively. CDDO-Im inhibits inflammatory response and tumor growth in vivo.