Lurbinectedin

Product Specifications

CAS Number

497871-47-3

Synonyms

PM-1183, LY-01017, Tryptamicidin, PM01183

SKU

C14353-1mg

Target

DNA/RNA Synthesis

Applications

Cell Cycle

Smiles

CC1=CC2=C (C3C4C5C6=C (C (=C7C (=C6C (N4C (C (C2) N3C) O) COC (=O) C8 (CS5) C9=C (CCN8) C2=C (N9) C=CC (=C2) OC) OCO7) C) OC (=O) C) C (=C1OC) O

Molecular Formula

C41H44N4O10S

Additionnal Information

Lurbinectedin, a DNA minor groove covalent binder with potent in vitro and in vivo anti-tumour activity. Lurbinectedin inhibits RMG1 and RMG2 cell growth with IC50 of 1.25 nM and 1.16 nM, respectively.

Storage Conditions

3 years -20°C powder

Available Sizes

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