Praeruptorin A
Product Specifications
CAS Number
73069-25-7
SKU
C14161-1mg
Target
Akt
Applications
PI3K/Akt/mTOR
Smiles
CC=C (C) C (=O) OC1C (C2=C (C=CC3=C2OC (=O) C=C3) OC1 (C) C) OC (=O) C
Molecular Formula
C21H22O7
Additionnal Information
Praeruptorin A, a naturally existing pyranocumarin, is isolated from the dried root of Peucedanum praeruptorum Dunn. Praeruptorin A inhibits p38/Akt-c-Fos-NFATc1 signaling and PLCγ-independent Ca2+ oscillation. Praeruptorin A can significantly upregulates multidrug resistance-associated protein 2 expression via the constitutive androstane receptor-mediated pathway in vitro, and this should be taken as an herb-drug interaction.
Storage Conditions
3 years -20°C powder
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