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Triptophenolide

Product Specifications

CAS Number

74285-86-2

Synonyms

Hypolide

SKU

C13895-1mg

Target

Androgen Receptor

Applications

Endocrinology & Hormones

Smiles

CC (C) C1=C (C2=C (C=C1) C3 (CCC4=C (C3CC2) COC4=O) C) O

Molecular Formula

C20H24O3

Additionnal Information

Triptophenolide (Hypolide), derived from Tripterygium wilfordii, is a pan-antagonist for wild-type and mutant androgen receptors with the IC50 values of 260 nM for AR-WT, 480 nM for AR-F876L, 388 nM for AR-T877A, and 437 nM for W741C+T877A.

Storage Conditions

3 years -20°C powder

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