Actinomycin D (Dactinomycin)

Product Specifications

CAS Number

50-76-0

Synonyms

Act D, RASP-101

SKU

C13823-10mg

Target

DNA/RNA Synthesis

Applications

Cell Cycle

Molecular Formula

C62H86N12O16

Additionnal Information

Actinomycin D (Dactinomycin, Act D, RASP-101) is a significant polypeptide antibiotic isolated from soil bacteria of the genus Streptomyces. Actinomycin D (Dactinomycin) inhibits DNA repair and rests the cell cycle at G1 phase with IC50 of 0.42 μM and 0.4 nM, respectively. Actinomycin D is an autophagy activator, induces p53-independent cell death and prolongs survival in high-risk chronic lymphocytic leukemia.This product is a hazardous chemical (acute toxicity/flammable/skin corrosive) . Please use it while wearing a protective face mask, gloves, and clothing.