Alobresib (GS-5829)
Product Specifications
CAS Number
1637771-14-2
SKU
C13820-2mg
Target
Epigenetic Reader Domain
Applications
Epigenetics
Smiles
CC1=C (C (=NO1) C) C2=CC (=C3C (=C2) NC (=N3) C4CC4) C (C5=CC=CC=N5) (C6=CC=CC=N6) O
Molecular Formula
C26H23N5O2
Additionnal Information
Alobresib (GS-5829) is a novel BET inhibitor that represents a highly effective therapeutics agent against recurrent/chemotherapy-resistant USC-overexpressing c-Myc. Alobresib (GS-5829) inhibits CLL cell proliferation and induces leukemia cell apoptosis through deregulation of key signaling pathways, such as BLK, AKT, ERK1/2, and MYC. Alobresib (GS-5829) also inhibits NF-κB signaling.
Storage Conditions
3 years -20°C powder
Available Sizes
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